There are five drugs in first line attack against tuberculosis. The durgs differ in their mechanism of action; whether they are bactericidal i.e. kill bacteria rapidly or bacteriostatic i.e. inhibits the multiplication and growth of bacteria but do not kill them. They also differ in their action against intracellular bacilli (those mycobacteria that are in the cell), extracellular bacilli (those mycobacteria that are outside the cell) and the bacilli in the lesion itself.
No single drug is effective in treating the disease but when used in combination, they can cure the disease. Here are the first line drugs used in treatment of tuberculosis.
All except streptomycin are given orally.
Isoniazid
It is bacteriostatic for resting bacilli but kills those which divide actively. It is active against intracellular bacilli, extracellular bacilli and bacilli at lesion. It has good penetration in cerebrospinal fluid and possesses good overall activity. Along with rifampicin, it is the main drug in treatment of tuberculosis. [Read more...]
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In medicine, early detection of the disease and treatment are key factors in successful management of the disease. If osteoarticular tuberculosis is diagnosed and treated at an early stage, the large majority of patients are expected to achieve healing with near normal function.
Synovial fluid is a thick, stringy fluid found in the cavities of synovial joints. It reduces friction between the articular cartilage and other tissues in joints by lubricating and cushioning them during movement.
After initial care of the patient with spinal injury, decision is made about the definitive care. A definitive care aims at making the injured spine stable and removing any decompression on the spinal cord.
