A second line drug for tuberculosis is either less effective than the first line drug or has an associated toxicity that makes second choice for use in tuberculosis patients.
Second class drugs are used when the patient either does not respond to first line or does not tolerate them and substantiating the treatment is necessary.
Following are second-line drugs used for the treatment of tuberculosis.
- Thioacetazone (T)
- P-aminosalicylic acid (PAS or P).
- Thioamides – Ethionamide, prothionamide
- Cycloserine
- Polypeptides- capreomycin, viomycin, enviomycin
- Aminoglycosides: e.g., amikacin (AMK), kanamycin (KM)
- Fluoroquinolones-Ciprofloxacin (CIP), levofloxacin, moxifloxacin (MXF), Ofloxacilin
Commonly used drugs are discussed below- [Read more...]
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