Orthopedic Care and Consultation
The US Food and Drug Administration has approved drug denosumab for use to prevention of to prevent skeletal complications in cancer patients with solid tumors and bone metastases.
The drug has already been approved and in market for postmenopausal osteoporosis.
The drug is used in different doses in in these two conditions. [Read more...]
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The United States Food and Drug Administration has approved duloxetine HCl delayed-release capsules for treatment of chronic musculoskeletal pain.
That gives many of the chronic pain patients another treatment option.
Duloxetine has been approved for both chronic low back pain and osteoarthritis. The decision was based on data from 4 double-blind, randomized clinical trials.
The recommended dose is 60 mg daily. [Read more...]
Popularity: 1% [?]
A research conducted by New York University have developed a method to use MRI to examine sodium ions in cartilage and view the development of osteoarthritis in knee joints.
This may provide a noninvasive method to diagnose osteoarthritis in its very early stages. It would also help to calculate measures of cartilage assessments.
The measurement reveal the location of glycosaminoglycans in cartilage tissues. Glycosaminoglycans serve as the building blocks of cartilage apart from other functions in the human body. [Read more...]
Popularity: 2% [?]
A new srudy has indicated that in athletes 14 years of age and younger with anterior cruciate ligament (ACL) tears, early reconstruction results in significantly improved outcomes without growth disturbance. A reconstruction done within 12 weeks of injury is defined as early reconstruction. In addition to better function the early intervention also saves money. [Read more...]
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Tuberculosis is a chronic infection that has made a worldwide resurgence due to advent of HIV and AIDS. In addition to this there is rise of drug-resistant mycobacterium tuberculosis which further threatens the global TB control efforts. Therefore it is very necessary to have diagnostic measures that detect resistance of the drugs to a particular strain fast. Conventional methods take months to detect the resistance and the search is on for new ways to detect the resistance or multi drug resistance in patients of tuberculosis. [Read more...]
Popularity: 2% [?]
Cochrane Database of Systematic Reviews has reported that topical nonsteroidal anti-inflammatory drugs may be safe and effective for acute musculoskeletal conditions in adults
The use of topical NSAIDs vary in different countries.In theory they have potential to provide pain relief without associated systemic adverse events.”
Recent report published on June 16,2010 has evaluated the evidence from randomized, double-blind, controlled trials of the efficacy and safety of topically applied NSAIDs for relief of acute pain. [Read more...]
Popularity: 1% [?]
Persistent pain after orthopaedic trauma is every troublesome and is a common phenomenon. Despite physical healing, some individuals continue to have persistent pain and disability and a reduced capacity for functioning.
A lot of research has been done to determine the factors responsible for persistent pain following injury.
Earlier studies suggested that factors other than the physical injury are important in the development of persistent pain.
A recent study involving 168 participants between 18-64 years evaluated the association between a range of biopsychosocial factors and the presence of persistent pain, pain severity, and pain interfering with normal work activities in a cohort of patients after of non-life-threatening orthopaedic injuries.
The study found that high initial pain, external attributions of responsibility for the injury, and psychological distress are factors that strongly predict persistent pain, pain-related work disability, and pain severity.
The study has been recently published in Journal of Pain.
Popularity: 1% [?]
A study conducted by University of California has pointed to the fact that patients who are taking proton pump inhibitors and histamine 2 receptor antagonists are at higher risk of developing hip fractures as compared to the patients who are not on the medications.
This was found in the study which involved 34000 patients with hip fractures taking proton-pump inhibitors and histamine-2 receptor antagonists shows that the risk for hip fracture is approximately 30% higher than in matched controls not taking these medications. [Read more...]
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In a recently published paper in march issue Archives of Internal Medicine, prevention of nonvertebral fractures with vitamin D is dose-dependent for individuals aged 65 years or older. The paper is based on meta-analysis of of randomized controlled trials.
Researchers found a significant positive trend between serum 25-hydroxyvitamin D concentrations and hip bone density and lower extremity strength. The reviewers identified 12 double-blind RCTs for nonvertebral fractures, enrolling a total of 42,279 subjects, and 8 RCTs for hip fractures, enrolling a total of 40,886 subjects, which compared the effects of oral vitamin D, with or without calcium, with those of calcium alone or of placebo. [Read more...]
Popularity: 1% [?]
A latest review by at Cochraine Library, an international nonprofit, independent organization that produces and disseminates systematic reviews of health care interventions, has concluded that removable splints and plaster casts appears to be equally safe and effective for treating minor “buckle” wrist fractures in children.
Buckle fracture or Torus fractures, are extremely common injuries seen in children. Because children have softer bones, one side of the bone may buckle upon itself without disrupting the other side; this is also known as an incomplete fracture.
The word torus is derived from the Latin word ‘Tori’ meaning swelling or protuberance. Children commonly sustain this injury by falling on an outstretched hand. [Read more...]
Popularity: 6% [?]
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