DiGeorge Syndrome is a genetic disorder caused by the deletion of a small section of chromosome 22. This results in a midline congenital defect including thymic aplasia, or congenital deficiency of a thymus.
Patients may present with a profound immunodeficiency disease, due to the lack of T cells. No other immune cell lineages are affected by the congenital absence of the thymus.
DiGeorge Syndrome is the most common congenital cause of thymic aplasia in humans.
DiGeorge Syndrome
DiGeorge syndrome is a hereditary disorder with unstable conditions present in every person suffering from this syndrome. However, conditions such as impacts on facial appearance, heart defects and underdeveloped or lack of parathyroid and thymus glands are generally observed in this syndrome.
[Link Moderated]