It constitutes the content of all intra-cerebral (inside the brain, cerebrum) ventricles, cisterns, and sulci (singular sulcus), as well as the central canal of the spinal cord.
It acts as a “cushion” or buffer for the cortex, providing a basic mechanical and immunological protection to the brain inside the skull.
It is produced in the choroid plexus in ventricles of brain.
Normal flow of CSF is required for normal functions of brain and spine.
Spinal anaesthesia or subarachnoid block involves pushing the drug into this space.