DiGeorge Syndrome is a genetic disorder caused by the deletion of a small section of chromosome 22. This results in a midline congenital defect including thymic aplasia, or congenital deficiency of a thymus.
Patients may present with a profound immunodeficiency disease, due to the lack of T cells. No other immune cell lineages are affected by the congenital absence of the thymus.
DiGeorge Syndrome is the most common congenital cause of thymic aplasia in humans.
Incoming search terms:
- I have digeorge syndrome (33)
- digeorge syndrome foot problems (2)
- broken bones and deletion 22 (1)
- scoliosis in patients with digeorge syndrome (1)
- scoliosis and degeorge syndrome (1)
- madelung deformity di george (1)
- does digeorge syndrome predispose bone breaks (1)
- digeorge syndrome orthopaedic (1)
- digeorge syndrome musculoskeletal (1)
- digeorge syndrome hip (1)