A compound called strontium ranelate may reduce back pain in women with osteoporosis and osteoarthritis of the spine, according to new study. The compound may also delay progression of spinal osteoarthritis.
Strontium ranelate has been shown to stimulate bone formation while inhibiting bone resorption.
Dr. Olivier Bruyere from University of Liege, Belgium and colleagues say their findings suggest that “strontium ranelate may have symptom- and structure-modifying effects in women with osteoporosis and osteoarthritis .”
The investigators reviewed the effects of 3 years’ treatment with strontium ranelate on the clinical and structural progression of spinal OA in 1105 women. As participants in the Spinal Osteoporosis Therapeutic Intervention and Treatment of Peripheral Osteoporosis trials, 566 women had received strontium ranelate and 539 had received placebo.
The researchers found that the proportion of women with worsening overall spinal OA score was reduced by 42 percent in the strontium ranelate group relative to the placebo group.
In addition, significantly more women in the strontium ranelate group saw improvement in back pain after 3 years compared with placebo. There were no significant between-group differences in health-related quality of life, however.
“This study has implications not only in the potential treatment of chronic back pain, but also for progression of OA at other sites,” the researchers conclude.
Strontium ranelate is indicated for the treatment of postmenopausal osteoporosis and has been shown to reduce the risk of fractures, Bruyere and colleagues note. They point out that strontium ranelate is also being studied in patients with OA of the knee.
The study was supported by a research grant from French pharmaceutical company Servier, which manufactures strontium ranelate.
Source: Medline Plus
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I had a lumbar disk replacement at L4-L5. It was performed on February 2008. It is not fusing as fast as the Doctor said that it should. I go back for my yearly in February 2009, I will take an xray and catscan with me so that he can see if the bone is fusing like it is suppose to. I started taking strontium citrate last week 680 daily. Would like to know what the chances are it could promote the bone to fuse? I am desparate to find ways so that the bone will fuse so that I do not have to have another back surgery.
Thanks for your time,
Kellye
I do not think Strontium does that. It is used for Osteoporosis.