Piriformis syndrome is one of the important causes of sciatica. In this neuromuscular disorder, the sciatic nerve is compressed or irritated by the piriformis muscle.
The symptoms are pain, tingling and numbness in the buttocks and along the path of the sciatic nerve descending down the lower thigh and into the leg.
The syndrome may occur due to anatomical variations in the muscle-nerve relationship, or from overuse or strain.
Piriformis syndrome should be considered as a possible diagnosis when sciatica occurs without a clear spinal cause.
Pathophysiology
The basic event is compression or irritation of the sciatic nerve. It is a kind of entrapment neuropathy.
Usually the sciatic nerve underneath the piriformis muscle. However, in 15-30% of the population the sciatic nerve passes through the substance of piriformis muscle. These people have a greater incidence of piriformis syndrome than does the general population.
Normally, piriformis acts as external rotator of the femur. It causes rotation at hip so as to turn foot pointing outward.
Overuse injury resulting in piriformis syndrome can result from activities performed in the sitting position that involves strenuous use of the legs as in rowing/sculling and bicycling.
Runners, bicyclists and other athletes engaging in forward-moving activities are particularly susceptible to developing piriformis syndrome.
Disproportionately weak hip abductors/gluteus medius muscles, combined with very tight adductor muscles, can cause the piriformis muscle to shorten and severely contract.
Piriformis muscle spasm can can result in impingement of not only the sciatic nerve but also the pudendal nerve (a nerve that controls the muscles of the bowels and bladder) and can lead to urinary and fecal incontinence.
Other proposed causes for piriformis syndrome are stiffness of the sacroiliac joints and overpronation of the foot or injury.
Piriformis syndrome is also known as “wallet sciatica” or “fat wallet syndrome,” as the condition can be caused or aggravated by sitting with a large wallet in the affected side’s rear pocket.
Diagnosis
Symptoms include radiating pain in the buttock, posterior thigh and lower leg. The pain is exacerbated with activity, prolonged sitting or walking.
Physical examination would reveal tenderness in the area of the sciatic notch.
The diagnosis is largely clinical and is one of exclusion. Other causes of sciatica should be ruled out.
CT, MRI, ultrasound, and electromyography are useful in excluding other conditions and help in reaching at a diagnosis.
Magnetic resonance neurography
It is a medical imaging technique that can show the presence of irritation of the sciatic nerve at the level of the sciatic notch where the nerve passes under the piriformis muscle.
Neurography can also determine whether or not a patient has a split sciatic nerve or a split piriformis muscle – this may be important in getting a good result from injections or surgery.
Treatment
- Non-steroidal anti-inflammatory drugs and/or muscle relaxants for pain relief
- Stretching exercises and massage,
- Avoidance of contributory activities as noted before
- Stretching exercises
- Local ice/heat
- Custom foot orthotics
- Gait correction
- Ultrasound to provide deeper heat
- Injections – steroids, botulinum toxin, lidocaine
- Surgery.


I had a tumor removed from my spinal cord,some of which they could not get all out of me.feering that it would cause alot more damage.the tumor was from c1 to c7.the surgery took over 16 hours.I was in the hospital for a month.my question is sence they left a small portion in me.Could the tumor grow again some time later on as I get older.This was in back in Oct,2004 please help me with some kind of an answer.because the doctor who performed the sergery wants nothing more to do with me.saying that it was like opening up pandoras box.