Examination of ultrastructural features of cellular and extracellular structures is a powerful diagnostic tool. The introduction of the transmission electron microscope in the early decades of the twentieth century dramatically expanded the investigative and diagnostic capabilities to study the submicroscopic details of diseased tissue including bone tumors and tumor like condition.
Use of the transmission through a thin section of tissue impregnated with electrondense material and embedded in plastic material and embedded in plastic medium is the most applicable for diagnostic purposes. [Read more...]
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