Use of Immunohistochemistry

cat_musculoskeletal_pathology.jpgImmunohistochemistry has become a generally accepted and widely used auxiliary method of diagnostic pathology, including the pathology of bone tumors and tumor like lesions.

This method has emerged as a diagnostically useful technique because of the development of highly specific antibodies and the invention of sensitive immune and enzymatic detection systems. The fluorescence detection methods are more often used in investigative studies and are rarely sued in diagnostic pathology. [Read more...]

Use of Electron Microscopy

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Examination of ultrastructural features of cellular and extracellular structures is a powerful diagnostic tool. The introduction of the transmission electron microscope in the early decades of the twentieth century dramatically expanded the investigative and diagnostic capabilities to study the submicroscopic details of diseased tissue including bone tumors and tumor like condition.

Use of the transmission through a thin section of tissue impregnated with electrondense material and embedded in plastic material and embedded in plastic medium is the most applicable for diagnostic purposes. [Read more...]