Anteroposterior and lateral views of knee replacement in 62 year old male.
Here is the AP view
Anteroposterior view of knee replacement
Here is the lateral view [Read more...]
New Method Developed For MRI To Detect Early Osteoarthritis In Knee
September 24, 2010 by Leave a Comment
A research conducted by New York University have developed a method to use MRI to examine sodium ions in cartilage and view the development of osteoarthritis in knee joints.
This may provide a noninvasive method to diagnose osteoarthritis in its very early stages. It would also help to calculate measures of cartilage assessments.
The measurement reveal the location of glycosaminoglycans in cartilage tissues. Glycosaminoglycans serve as the building blocks of cartilage apart from other functions in the human body. [Read more...]
Xray of Bilateral Medial Compartment Osteoarthritis of knee
July 28, 2009 by Leave a Comment
Osteoarthritis of knee is very common problem in Asian region. The disease typically starts in medial compartment of the knee and then progresses to all the compartments.
OA bilateral knee
The xray belongs to a lady of 49 years old whose main complaint was pain on climbing stairs. An xray doen revealed bilateral medial compartment involvement.
The patient is being managed on conservative treatment.
Single Intraarticular Anakinra Injection Not Effective For Osteoarthritis
April 23, 2009 by 2 Comments
Anakinra is an interleukin-1 (IL-1) receptor antagonist and is common;y used for treatment of rheumatoid arthritis. Anakinra blocks the biologic activity of naturally occurring IL-1 by competitively inhibiting the binding of IL-1 to the Interleukin-1 type receptor.
IL-1 is produced in response to inflammatory stimuli and mediates various physiologic responses, including inflammatory and immunologic reactions. IL-1 stimulates bone resorption and induces tissue damage like cartilage degradation as a result of loss of proteoglycans.
The anakinra molecule is a recombinant, non-glycosylated version of human IL-1 receptor antagonist prepared from cultures of genetically modified Escherichia coli using recombinant DNA technology.
The drug is used as biological response modifier. [Read more...]
Height Gene Linked To Osteoarthritis Too
April 16, 2008 by Leave a Comment
Common genetic variants associated with osteoarthritis may also play a role in determining a person’s height, according to a U.S.-European study which included an analysis of the genomes of more than 35,000 people.
Many genes control height, but only a few are associated with osteoarthritis.
The findings also add to overall understanding of height. [Read more...]
Glucosamine No Good For Hip Arthritis-Study
March 27, 2008 by Leave a Comment
Glucosamine sulfate, a popular dietary supplement purported to ease the pain and inflammation of arthritis, does not seem to help people with arthritis in their hips.
That’s the conclusion of a study that compared the use of glucosamine to a placebo for the treatment of mild to moderate hip arthritis. [Read more...]
Strontium Ranelate May Reduce Backpain In Osteoarthritis of spine
March 26, 2008 by 2 Comments
A compound called strontium ranelate may reduce back pain in women with osteoporosis and osteoarthritis of the spine, according to new study. The compound may also delay progression of spinal osteoarthritis. [Read more...]
Psoriatic Arthritis-Laboratory Findings, Diagnosis and Treatment
March 17, 2008 by 1 Comment
In Psoriatic arthritis, there are few laboratory abnormalities. Elevated erythrocyte sedimentation rates, C-reactive proteins and complement levels reflect inflammation. Rheumatoid factors are uncommon and are more likely to be observed in those with symmetric arthritis. Immunoglobulin levels, especially IgA levels, may be elevated.
Uric acid levels may be elevated; sodium urate crystals in joint fluids suggest gout.
Radiologic investigation reveals findings similar to those of rheumatoid arthritis, soft tissue swelling, loss of the cartilage space, erosions, bony ankylosis of fingers, subluxations, and subchondral cysts. There is less demineralization.
Following features if present are suggestive of psoriatic arthritis
- Erosions at DIP joints
- Expansions and cuplike erosions of and bony proliferation of the distal terminal phalanx
- Proliferation of bone near osseoperiostitis, and telescoping of one bone into its neighbor [Read more...]
Psoriatic Arthritis-Symptoms and Presentation
March 17, 2008 by Leave a Comment
Psoriatic arthritis is chronic inflammatory arthritis that affects 5 to 42 percent of people with psoriasis.As of now, the cause and pathogenesis of psoriatic arthritis are unknown. There are indirect evidence that infections, trauma, increased cellular immunity to streptococci, decreased suppressor cell activation, immune complexes, complement activation, adhesion molecules, dendritic cells, keratinocytes, and abnormal fibroblast and polyamorphonuclear leukocyte function may play a role. [Read more...]
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